Liquid paraffin, also known as paraffinum liquidum, is a very highly refined mineral oil used in cosmetics and for medical purposes. This is a UK definition (British Pharmacopoeia) and the term may have different uses in other countries. The cosmetic or medicinal liquid paraffin should not be confused with the paraffin (or kerosene) used as a fuel.
The term paraffinum perliquidum is sometimes used to denote light liquid paraffin. Conversely, the term paraffinum subliquidum is sometimes used to denote a thicker (more viscous/oily) mineral oil.
Video Liquid paraffin (drug)
Usage and side effects orally as laxative
Liquid paraffin is considered to have a limited usefulness as an occasional laxative, but is unsuitable for regular use as it can seep from the anus and cause irritation.
Efficacy of liquid paraffin is suggested by 2016 Cochrane review.
It might interfere with the absorption of fat-soluble vitamins, though evidences seem low.
It can be absorbed into the intestinal wall, and may cause foreign-body granulomatous reactions in some rat species but not in others and that reaction might not occur with human.
There are evidences suggesting the lack of carcinogenicity.
If it enters the lungs, it can cause lipoid pneumonia.
Liquid paraffin is also used in combination with magnesium as an osmotic laxative, sold under the trade name Mil-Par (among others).
Maps Liquid paraffin (drug)
Side effects if injected
Causes granulomatous reactions if injected.
See also
- Petroleum jelly
References
Source of article : Wikipedia
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